Abstract
1. 1. Administration of multiple or single doses of sodium fluoroacetate (1080) to male Tiliqua rugosa caused a decrease in plasma testosterone concentration. 2. 2. A single dose of 100 or 250 mg 1080 kg −1 body weight decreased plasma testosterone by 52%. However, 25 mg kg −1 had little apparent effect on testosterone levels. When lizards were given the multiple dose equivalent of these doses over 12 days at 3 day intervals, the effect was much less dramatic with plasma testosterone concentration steadily declining over 15 days for the two higher doses. 3. 3. There was a suggestion of degeneration of seminiferous tubules in some individuals.
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