Abstract
Rapid and complete soft tissue healing after tooth extraction minimizes surgical complications and facilitates subsequent implant placement. We used four treatment methods and assessed changes in soft tissue socket closure following tooth extraction in humans. The effects of platelet-rich fibrin-calcium sulfate hemihydrate (PRF-CSH), platelet-rich plasma-calcium sulfate hemihydrate (PRP-CSH), a resorbable collagen dressing (RCD), and no grafting material were compared in a randomized, controlled pilot study with a blinded parallel design (N = 23). Patients with a hopeless tooth scheduled for extraction were randomly assigned to one of the four treatment groups. Socket measurements were obtained immediately after extraction and treatment, as well as after 21 days. There was a significant decrease in the total epithelialized external surface area of the extraction sockets in each group at all time points. However, there were no significant differences in soft tissue closure (p > 0.05) at any time point and PRF-CSH or PRP-CSH did not provide any additional benefit to enhance the soft tissue closure of extraction sockets compared with either RCD or sites without graft.
Highlights
Tooth extraction leads to vertical and horizontal ridge resorption that can make implant placement difficult or impossible [1]
It is well established that post-extraction ridge preservation can be beneficial prior to implant placement [1,2]
All groups were healing without complication at 21 days. This result is consistent with wound healing post-extraction when no graft is placed
Summary
Tooth extraction leads to vertical and horizontal ridge resorption that can make implant placement difficult or impossible [1]. It is well established that post-extraction ridge preservation can be beneficial prior to implant placement [1,2]. Some studies have shown that ridge preservation does not completely prevent bone loss post-extraction, such procedures aid in reducing the extent of that loss [3]. Ridge preservation can be performed using a variety of materials. Graft materials provide osteogenic, osteoinductive, and/or osteoconductive properties, and provide mechanical support and supply a framework for osteogenic cells to stimulate bone production [4]. Rapid socket closure and re-epithelialization may assist in graft retention and exclusion of debris, as well as improve patient comfort
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