Abstract
Abstract An experimental study on 200 guinea pigs was carried out to analyze the amino acid pattern and their distribution among plasma, cerebrospinal fluid and brain tissue in acute phenethylhydrazine poisoning. The amino acid pattern in the various fluids and tissues was strongly modified and the free amino acid distribution between plasma and cerebrospinal fluid, plasma and brain tissue, and brain tissue and cerebrospinal fluid differed significantly from control values. Hypotheses about the particular cerebral metabolic pathways involved are presented.
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