Abstract
Earlier, the data on the ability of laminin-332 to protect liver cancer cells from apoptosis caused by doxorubicin, sorafenib, and gefitinib have been obtained. In order to answer the question whether this action of laminins is common for cancer cells of other types, we estimated the effect of several laminin isoforms on the survival of two colorectal cancer cell lines (RKO and SW-480) when treated with chemotherapeutic agents used in the colon cancer therapy (5-fluorouracil, regorafenib, and sorafenib). The data obtained suggest that this action of laminins is not universal and is likely governed by individual features of cancer cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
