Abstract
Background: Nowadays, iron nanoparticles and other nanomaterials are widely used in many fields including industrial and biomedical fields. Yet many concerns remain about their fate and toxicity to living organisms. Objective: The aim of the current study was to evaluate the risk of using iron oxide nanomaterials as food additives for animals to increase its utilization compared to bulk size particles of the same material. Materials and Methods: The study included the effect of two different nano-sized iron oxides (25 nm and 50 nm) at two doses (1 mg/kg feed and 10 mg/kg feed) on some biological and hematological parameters in male albino rats. Results: The results indicate that rat’s performance, growth, feed conversion rates were not affected with no sign of toxicity. Most of the hematological parameters in all treated groups were not affected by IONPs except one group which showed a significant difference in the percent of granulocytes compared with the control. Conclusion: It can be concluded that iron oxide NPs of different sizes and doses did not affect their performance, growth rate, hematological parameters with no sign of toxicity.
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