Abstract

1. Injecting noradrenaline (3 μg/kg body wt) into a lateral ventricle of the brain of oxen exposed to cold environmental conditions (−1°C and wind speed 120 m/min) resulted in a fall in plasma unesterified fatty acid concentration, oxygen consumption and rectal temperature. 2. This effect on oxygen consumption and rectal temperature was not apparent in animals given intraventricular noradrenaline together with a simultaneous intravenous infusion of noradrenaline (0.3 μg/kg min). In these circumstances the plasma unesterified fatty acid concentration was raised. 3. It is concluded that intraventricular injection of noradrenaline results in inhibition of fat mobilization, which may in turn inhibit heat production of oxen in a cold environment.

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