Abstract
The study aims to observe the diffusion process which is influenced by different velocity and fluid concentrations. Using a microfluidic system and the diffusion process through a reverse osmosis membrane. The research was carried out by flowing fluid into the microchannel. The diffusion process is known by measuring and analyzing the density of liquid waste aquades-trimethylene glycol. The results showed the amount of diffusion through the membrane was influenced by flow velocity and fluid concentration. this is because the velocity of the flow produces pressure on the wall so that it pushes the fluid to diffuse through the membrane.
Highlights
The microchannel is one of the new technologies in the pharmaceutical field
The Microchannel applications include mixer, microreactor, and cytotoxity. This is related to chemical reactions at a micro-scale that is faster with a small volume and a short diffusion process to allow faster fluid mixing
This research was conducted to determine the effect of flow velocity and concentration on the diffusion of Trimethylene glycol through a reverse osmosis membrane in a microchannel
Summary
The microchannel is one of the new technologies in the pharmaceutical field. In the pharmaceutical field, the microchannel is assumed to be a blood vessel of a living thing [1]–[3]. The two channels on the microchannel that are insulated with a membrane represent external and internal fluids in human cells. Diffusion that occurs through a porous membrane describes the process of absorption of nutrients or drugs that enter the body through the blood [9]. The Microchannel applications include mixer, microreactor, and cytotoxity This is related to chemical reactions at a micro-scale that is faster with a small volume and a short diffusion process to allow faster fluid mixing. Channel proteins have holes or pores for the process of diffusion of substances from the digestive tract into body cells, but not all substances in the digestive tract can penetrate the membrane through this mechanism [16], [26], [27]. The size of the membrane pore radius used in the experiment was 1.095 μm
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