The effect of esmolol on children's heart rate who accept squint correction and adrenaline eye drop

Abstract

Objective To observe the effect of esmolol on children's heart rate who accept squint correction and adrenaline eye drop.Methods Selected six to ten years old children with squint correction of 90 cases were randomly divided into three groups,each group had 30 cases.Group A was control group and accepted 0.9％ physiological saline to sick eye.Group B dropped the adrenaline to sick eye.Group C dropped the adrenaline to sick eye and accepted intravenous injection esmolol antagonist.Monitored and recorded the heart rate before children came into the operating room.The basic value was T0.Before anesthesia was T1,5 minutes after anesthesia was T2,sick eye accepted adrenaline,or at the same time to intravenous injection esmolol then 2 minutes was T3,5 minutes was T4,10 minutes was T5 and 60 minutes was T6.Results The difference of heart rate change (T0-T2) in three groups was not statistically significant.Compared heart rate (T3-T5) of each time point in group B and C with group A,the difference was statistically significant.But heart rate rise (T3-T5) in group C was significantly lower than in group B,the difference was statistically significant.Conclusions During strabismus correction,dropped the adrenaline to sick eye can make the heart rate rise significantly moment,intravenous injection esmolol can significantly inhibit its rise and maintain children's perioperative heart rate steady. Key words: Adrenaline; Esmolol; Squint correction; Heart rate