The effect of eight weeks of Pilates with curcumin supplementation on liver enzymes and lipid profile in overweight and obese women

Abstract

The current randomized, double-blind, clinical trial aimed to evaluate the effects of a 8-week curcumin supplementation plus Pilates training on liver enzymes level and lipid profile in overweight and obese females. 60 overweight and obese females randomly enrolled in this clinical trial with a four-group design which receiving one capsule containing 47.5 mg of curcumin or placebo daily with or without Pilates training for 8 weeks. Serum level of ALT, AST, LDL-C, HDL-C, T-Chol and TG were analyzed before and 24 h after the intervention. Pairwise t -test and MANCOVA were used for data analyzes. The results showed that weight, BMI, WHR and PBF decreased in the curcumin + Pilates group compared to the other groups (P < 0.05). According to the results, an 8-week Pilates and curcumin alone or in combination reduced serum ALT, LDL-C, TG and T-Chol (P < 0.01) compared with the control group. Also, serum AST levels decreased from 23.75 ± 2.14 to 19.37 ± 1.98 in the curcumin group (P = 0.017). Eight weeks of intervention with Pilates and curcumin alone or in combination seemed effective in improving lipid profile and reducing ALT enzyme levels in overweight and obese females. It also appears that the AST enzyme is only affected by curcumin supplementation. • Pilates training plus Curcumin supplement significantly decreased anthropometry indices. • Pilates and Curcumin alone or in combination led to significant changes in lipid profile. • Curcumin supplement significantly improve liver enzymes.