Abstract
Deep brain stimulation (DBS) has repeatedly been shown to be beneficial in controlling motor symptoms in Parkinson's disease (PD). For non-motor symptoms, a positive effect of DBS on mood, sleep disorders, impulse control disorders and psychotic experiences has been suggested. However, patients undergoing DBS often have a significant decrease in dopaminergic medication, which could also underlie changes in non-motor symptoms.The purpose of this study was to evaluate the effect of DBS surgery with corresponding change in medication on the psychiatric non-motor symptoms in PD patients.
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