Abstract
The bitter melon plant (Momordica charantia L) has medicinal properties. Bitter melon leaves contain secondary metabolites such as flavonoids, tannins, saponins, and alkaloids. The compound has anti-fungal properties. This study aims to determine the effect of ethanol extract of bitter melon leaves (Momordica charanthia L) on the inhibition zone of the fungus Trichophyton rubrum diffusion method. The research method used was a quasi-experiment with a purposive sampling technique. The population in this study were bitter melon extract made with criteria of old leaves (obtained from bitter melon plants), 5th leaf from shoot to base, green leaves, non-rot leaves, non-ripped leaves and not eaten by caterpillars that have taken in Rasau Jaya Village 1, Rasau Jaya District, Bina Karya Hamlet. The sample used in this study was pared leaf extract (Momordica charantia L) using ethanol solvent with a concentration of 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80% and 90% using Dimethyl Sulfoxide as thinner. Analysis of the Linear Regression Test obtained the value (p = 0.00 <0.05), then Ha was accepted meaning that there was an influence of ethanol extract of the bitter melon leaf (Momordica charantia L) on the inhibition zone of the fungus Trichophyton rubrum by the diffusion method. The results of R Square (R2) which amounted to 0.930 showed that the magnitude of the contribution of the concentration of bitter melon leaf extract in influencing the inhibitory zone of the fungus Trichophyton rubrum was 93%.
Highlights
This study aims to determine the effect of ethanol extract of bitter melon leaves (Momordica charanthia L) on the inhibition zone of the fungus Trichophyton rubrum diffusion method
Hasil penelitian ini berbeda dengan penelitian yang dilakukan oleh Jagessar, Mohamed dan Gomes (2008) yang menunjukkan bahwa ekstrak etanol daun pare dapat menghambat pertumbuhan jamur Candida albicans dengan memilki zona hambat sebesar 75 x 45 mm menggunakan metode sumuran terbentuk zona hambat yang sama dengan kontrol positif
Summary
Direndam dalam sampel yang telah diencerkan pada berbagai konsentrasi selama 15 menit. 2.5 Analisis Data Data yang diperoleh dari hasil penelitian kemudian dianalisis secara komputerisasi menggunakan Program SPSS. Biasanya melalui prosedur bertahap antara lain (Sujarweni, 2014). Analisis univariat adalah analisa yang dilakukan menganalisis tiap variabel dari hasil penelitian. Analisis univariat berfungsi untuk meringkas kumpulan data hasil pengukuran sedemikian rupa sehingga kumpulan data tersebut berubah menjadi informasi yang berguna dan pengolahan datanya hanya satu variabel saja sehingga dinamakan univariat. Yang termasuk analisis univariat tersebut adalah statistik deskriptif. Dalam analisis univariat data diolah untuk mengetahui gambaran dari tiapkonsentrasi seperti nilai maksimum, nilai minimum, rata-rata (mean) dan standar deviasi. Analisis bivariat adalah analisa yang dilakukan lebih dari dua variabel. Analisa bivariat berfungsi untuk mengetahui hubungan antar variabel. Data yang diperoleh dari hasil penelitian akan dianalisis dengan menggunakan Uji Regresi Linier yang diolah secara komputerisasi menggunakan program komputer.
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