Abstract

Background: The effects of pulmonary rehabilitation in patients with asthma and obesity are largely unknown. Objective: To compare the effects of an outpatient pulmonary rehabilitation (PR) program on exercise tolerance and asthma control in obese and non-obese asthmatics. Methods: Non-obese (BMI Results: A total of 138 asthma patients were included in this study. Fifty-two patients were obese (BMI 25.4, FEV1 90%) and 85 patients were non–obese (BMI 35.0, FEV1 90%). At baseline, obese asthma patients had a lower level of exercise tolerance reflected by a lower 6MWD (525m vs 621m, p Conclusion: our results suggest that a standardized PR program is feasible in obese asthmatics and that they benefit as much as non-obese asthma patients. It is unclear whether an adapted lifestyle program with emphasis on weight loss and self-management strategies could improve the effects on exercise capacity, asthma control and quality of life these obese asthmatics.

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