Abstract

Background: The infection by hepatitis C virus causedliver diseases such as:chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The current study aims to investigate the rate of HCV genotypes, subtypes, viral load and antibody immune response among Iraqi chronic hepatitis patients.Methodology: During 2012-2017 period seventy-hundred and twenty tow hepatitis patients were referred to Middle East Laboratory from Baghdad and other provinces asking for HCV viral load, its genotype and anti-HCV antibody determination.Results: A cross six years records, HCV genotype 4 was the most prevalent among Iraqi chronic hepatitis patients (46.68%), then genotype 1 (37.12%).There is notable changes in HCV genotypes distribution especially during 2017, where the genotype 1 predominantly found (52.63%). Although, these genotypes were none significantly associated with gender, age, viral load or anti-HCV antibody.Conclusion: This recordindicates a recent change in the rate of HCV genotype 1 over genotype 4 infection in Iraqi chronic hepatitis patients.

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