Abstract

SUMMARYRabbits and mice, but not sheep, guinea-pigs or rats, were suitable hosts for secondary echinococcosis using protoscoleces obtained from Australian sheep. The host specificity is tentatively related to the phylogenetic relationship between the donor host and receptor host.The development rate of hydatid cysts in mice is described in terms of increase in fresh weight, dry weight, and maximum cyst diameter. Fertile cysts were found after 8 months when the water content of the cysts had increased to more than 95 %. The diameter of fertile cysts up to 14 months ranged from 6 to 30 mm. By 14 months, the average fresh weight of cysts was greater than the body weight of the mice.This work was carried out during the tenure of an Australian Wool Board Senior Postgraduate Scholarship, and forms part of a thesis to be presented for the degree of Doctor of Philosophy of the Australian National University.I wish to thank my supervisor, Professor J. D. Smyth, for guidance and criticism.

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