Abstract

BackgroundDeep vein thrombosis (DVT) of lower limb is one of the common complications after total hip arthroplasty(THA), we aimed to evaluate the potential risk factors of DVT of lower limb in patients with THA, to provide insights into the management of THA.MethodsPatients who underwent THA in our hospital from January 1, 2017 to November 30, 2020 were included. The personal characteristics and clinical data of DVT and no-DVT patients were compared and analyzed. Logistic regression analyses were perfomed to identify the potential risk factors of DVT in patients with THA.ResultsA total of 182 THA patients were included, the incidence of DVT of lower limb in patients with THA was 19.78 %. There were significant differences in the age, BMI, diabetes, number of replacement, duration of surgery, type of prosthesis and duration of days in bed between DVT and no-DVT patients(all P < 0.05). And there were no significant differences in the gender, hypertension, hyperlipidemia, preoperative D-dimer, type of anesthesia and anticoagulant drugs use(all P > 0.05). Logistic regression analysis indicated that age > 70y(OR4.406, 95 %CI1.744 ~ 6.134), BMI ≥ 28(OR2.275, 95 %CI1.181 ~ 4.531), diabetes(OR3.949, 95 %CI1.284 ~ 5.279), bilateral joint replacements(OR2.272, 95 %CI1.402 ~ 4.423), duration of surgery ≥ 120 min(OR3.081, 95 %CI1.293 ~ 5.308), cemented prosthesis(OR2.435, 95 %CI1.104 ~ 4.315), and duration of days in bed > 3 days(OR1.566, 95 %CI1.182 ~ 1.994) were the risk factors of DVT of lower limb in patients with THA.ConclusionsDVT in the lower limb after THA is common, and its onset is affected by many factors. In clinical work, attention should be paid to identify the risk factors for DVT and targeted interventions are highlighted to prevent the postoperative DVT.

Highlights

  • Deep vein thrombosis (DVT) of lower limb is one of the common complications after total hip arthroplasty(THA), we aimed to evaluate the potential risk factors of DVT of lower limb in patients with Total hip arthroplasty (THA), to provide insights into the management of THA

  • The exclusion criteria for patients were: (1) the pathological fractures caused by malignant tumors, tuberculosis which might influence the development of DVT; (2) DVT of the lower extremities existed before THA; (3) patients who disagreed to participate in this study

  • Experts from the Chinese Obesity Working Group considered that BMI ≥ 28 kg/m2 is more appropriate for obesity[33], this study used the standard of BMI ≥ 28 kg/ m2, the results have showed that BMI ≥ 28 kg/m2 is a risk factor affecting the occurrence of DVT

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Summary

Introduction

Deep vein thrombosis (DVT) of lower limb is one of the common complications after total hip arthroplasty(THA), we aimed to evaluate the potential risk factors of DVT of lower limb in patients with THA, to provide insights into the management of THA. The formation of DVT of the lower extremities can increase the suffering of patients, prolong hospitalization time, and increase medical expenses[8]. Once it falls off, it can cause pulmonary embolism, and severe cases can lead to death. It is necessary to further explore the related risk factors In this present study, we aimed to evaluate the influencing factors of DVT of lower limb after THA, to provide evidence support for the prevention and treatment of clinical THA

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