Abstract

This volume as a whole describes enzyme induction mechanisms and the influences of enzyme induction upon metabolism and its control. The present chapter deals with various ways in which the metabolism of a single amino acid tryptophan is controlled. While processes influencing this include induction, the de novo synthesis of enzymes which metabolize tryptophan is only one of a variety of ways in which its metabolism is apportioned between various pathways. For example, altered activity of existing enzyme molecules and altered availability of plasma tryptophan for metabolism are also important. The roles of these factors will therefore be discussed as well as that of induction. Mechanisms of a less specific nature such as altered availability of tissue amino acid pools are described in detail elsewhere (Munro, 1970) and will not be dealt with here.KeywordsTryptophan MetabolismTryptophan LevelTryptophan ConcentrationPlasma TryptophanFree TryptophanThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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