Abstract
The base composition of DNA isolated from different organs (tissues) of some invertebrates, fishes, amphibia, reptiles, birds and mammals has been studied. The G + C content in the DNA studied varies from 37.0 to 50.9 mole %. The rare base, 5-methylcytosine, has been found in all animal DNA. The content of 5-methylcytosine in these DNAs varies from 0.65 to 2.61 mole %. A positive correlation between the G + C and 5-methylcytosine contents in the DNA of animals belonging to one class is observed. The content of 5-methylcytosine is species and tissue specific. It is believed that the tissue differences with regard to the 5-methylcytosine content in the DNA of the organism are due to the various levels and specific character of DNA methylation.
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Schedule a callMore From: Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
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