The Comparison of Reconstruction Algorithms for Diffuse Optical Tomography

Abstract

Diffuse optical tomography (DOT) utilizes wavelength range of 750-950 nm to map the spatial distribution of the tissue chromophores of breast tissue for cancer diagnosis or follow up prognosis. DOT allows tomographic reconstructions of tissue optical properties. Several reconstruction methods have been developed to minimize artifacts and obtain more realistic tomographic images. In order to compare four different reconstruction algorithms, data acquired from tissue phantoms using a DOT system. Algebraic reconstruction technique (ART), simultaneous iteration reconstruction technique (SIRT), truncated singular value decomposition (TSVD) and truncated conjugate gradient (TCG) techniques have been compared in terms of location of inclusion in the tissue phantoms. It has been shown that images reconstructed by the subspace techniques, TSVD and TCG locating the inclusion position better than the algebraic methods ART and SIRT. Beside, images reconstructed by TSVD and TCG have less artifact when compared to images of ART and SIRT.