The comparison of prognostic value among ankle brachial pressure index, arterial stiffness and pressure wave reflection in subjects with coronary artery disease

Abstract

ObjectivesThe present retrospective study was conducted to compare the prognostic value among ankle brachial pressure index (ABI), brachial-ankle pulse wave velocity (baPWV,) and radial augmentation index (rAI) in patients with coronary artery disease (CAD).MethodsABI, baPWV and rAI were measured in consecutive patients admitted for the management of CAD into our medical university hospital (n = 821, 677 males and 144 females; age 65.4 ± 10.5 years old), and they were followed at the outpatient department. During the follow-up period, events were defined as in-stent restenosis, new lesion of coronary artery sclerosis and MACE (i.e., acute coronary syndrome, cerebral infarction, cerebral bleeding and cardiac death).ResultsAmong the study period (4.2 ± 3.0 years), the event of in stent restenosis (n = 99), new lesion of coronary artery sclerosis (n = 77) and MACE (n = 18) were observed respectively. In cox regression analysis after adjustment of age and gender, baPWV > 18m/sec, but not ABI18 m/sec) had significantly higher incidence of MACE (P = 0.021)(Figure). Both baPWV >18 m/sec (odds 1.61: 95% CI: 1.01 – 2.56, p = 0.044) and ABI