The Clinical analysis of sepsis caused by community acquired pseudomonas aeruginosa infection in infants.

Abstract

Objective To analyze the clinical features of sepsis caused by community acquired pseudomonas aeruginosa infection. Methods We analyzed retrospectively the pictures of 12 cases with sep-sis infected by community acquired pseudomonas aeruginosa in Children's Hospital of Fudan University from May 2003 to May 2007. Results Twelve cases were healthy before these episodes. Their symptoms devel-oped quickly within 1 to 5 days and presented with endotoxiemia (12 cases) ,high fever (12 cases) ,septic shock (6 cases), severe pneumonia (12 cases) and atopic dermatitis (6 cases). Their features progressed rapidly and 1 to 6 organs dysfunction occurred. Bacteria culture of serum and exudates had a high positive rate. Drug sensitivity test showed the pseudomonas aeruginosa from community were sensitive to the majority of anti-gram positive antibodies except SMZco. Six cases died at last. Conclusion Pseudomonas aeruginosa sepsis has a low incidence in children, but their clinical features deteriorate rapidly, and are subject to multiple organ dysfunction. Early diagnose and early intervention are the keys to treatment. Key words: Pseudomonas aeruginosa; Community acquired infection; Children; Sepsis