Abstract
In the present study, the chemical composition of the essential oil (EO) obtained from the flowers of Abeliophyllum distichum, commonly known as white forsythia, was examined by gas chromatography-mass spectrometry (GC/MS). Thirty-five components including epoxy linalool, methyl salicylate, linalool oxide (pyranoid), and L-linalool were identified in the EO of A. distichum flowers (AfEO). In addition, the AfEO exhibited a remarkable anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. We found that this anti-inflammatory effect was mediated by inhibiting the expression of proinflammatory mediators, including IL-1?, IL-6, and IL-18. Taken together, these results confirm the potential use of the AfEO as an anti-inflammatory agent for topical application.
Highlights
Essential oils (EOs) obtained from several plant organs are a mixture of various aromatic chemicals belonging to different chemical families, including terpenes, aldehydes, alcohols, esters, phenolic, ethers, and ketones (Leyva-López et al 2017)
EOs are known to play a crucial role in protecting against many pathogens and arthropod pests as well as in facilitating communication between plants (Kumar et al 2018), they have been extensively utilized in the perfume, cosmetics, pharmaceutical, and food industries because of their unique flavour and fragrance and biological activities (Swamy et al 2016)
We studied the inhibitory effect of the AfEO on NO production in the LPS-stimulated RAW 264.7 cells
Summary
Essential oils (EOs) obtained from several plant organs are a mixture of various aromatic chemicals belonging to different chemical families, including terpenes, aldehydes, alcohols, esters, phenolic, ethers, and ketones (Leyva-López et al 2017). A total of 35 components including epoxy linalool, methyl salicylate, linalool oxide (pyranoid), and L-linalool were identified from the AfEO (Table 2). The composition of EO differs according to the growth conditions, harvesting time, and extraction method (Daferera et al 2000), linalool should be a characteristic compound of the Abeliophyllum and Forsythia species.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
