Abstract
The mechanical properties of compressed beam specimens of microcrystalline cellulose (Avicel pH 101) have been assessed in terms of the tensile strength (sigma t), Young's modulus (E) and the following fracture mechanics parameters: the critical stress intensity factor (KIC), the critical strain energy release rate (GIC) and the fracture toughness (R). Increase in the compaction pressure used to form the beams resulted in compacts with higher values of tensile strength, Young's modulus, KIC, GIC and R, indicating that the compacts became less brittle as their porosity decreased. Extrapolation of the values of sigma t, E, KIC, GIC and R to provide values at zero porosity indicated that the material had values of 30 Nm m-2, 0.0103 GPa, 1.21 MN m-3/2, 1.98 x 10(2) Nm-1 and 2.19 x 10(3) Nm-1, respectively. These provide a range of values whereby a fuller characterization of the mechanical properties of pharmaceutical materials can be made.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
