Abstract
The Giant central cell granuloma (GCCG) is a benign intra-osseous lesion of the neo-plastic type. It appears mainly in the mandible, but can be observed in the maxilla and small bones of the hand and foot, with a predilection for the female sex and prevalence at a young age. Its diagnosis is clinical and radiological, confirmed by histological examination. The differential diagnosis is biological because it has a wide range of morphologies and a misinterpretation with other giant cell lesions can often occur. The authors present a case of the Giant central cell granuloma in a 62-year-old woman developing for 3 years after dental extractions. The most favorable treatment for giant cell granulomas is surgical whose main objective is to prevent recurrences.
Highlights
The repairing giant cell granuloma was first described by Jaff in 1953 [1] as the central type giant cell granuloma, which is commonly defined as an intra-osseous lesion consisting of cellular fibrous tissue containing several foci of hemorrhage, multinucleated giant cells and occasional trabeculae of woven bone [2]
This lesion falls within a structure of giant cell tumors and pseudo-tumors, classified as follows: cherubism, central giant cell granuloma, and aneurysmal cyst
It is identical to the central giant cell granuloma
Summary
The repairing giant cell granuloma was first described by Jaff in 1953 [1] as the central type giant cell granuloma, which is commonly defined as an intra-osseous lesion consisting of cellular fibrous tissue containing several foci of hemorrhage, multinucleated giant cells and occasional trabeculae of woven bone [2]. Associated with it are two other types of lesions characterized by the existence of giant cells: Giant cell tumor; brown hyperparathyroid tumors [3]. It is characterized histologically by an exuberant proliferation of multinucleated giant cells [7]. Integr J Med Sci.2021;8:1-4 diagnosis, despite being rare, of a brown tumor due to hyperparathyroidism with a usually histological appearance.
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