Abstract
No Abstract Available
Highlights
While HIV invades the brain early in the course of HIV infection,[1] severe mental illness probably only occurs later in the disease.[2]
INVESTIGATION n In a case where severe behavioural disturbance is present in a setting of severe immunocompromise, investigations should include basic blood work-up, as well as lumbar puncture and a computed tomography scan of the brain. n If confusion is prominent and/or the patient has a headache and/or fever, it is prudent to request polymerase chain reaction (PCR) testing of the cerebrospinal fluid for cytomegalovirus, herpes simplex virus, Epstein-Barr virus and JC virus
One case series reported a 2% incidence of new-onset psychosis in patients presenting with an AIDS-defining diagnosis
Summary
While HIV invades the brain early in the course of HIV infection,[1] severe mental illness probably only occurs later in the disease.[2]. A working diagnosis of psychosis secondary to HIV was made. INVESTIGATION n In a case where severe behavioural disturbance is present in a setting of severe immunocompromise, investigations should include basic blood work-up, as well as lumbar puncture and a computed tomography scan of the brain.
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