Abstract
Urinary tract infections are most significant cause of disease in females and children. Homoeopathic mother tinctures are clinically used for the management of different pathological conditions however; there are several controversial theories for their effectiveness. The objective of this study was to assess the antibacterial effect of Uva ursi tincture in comparison with antibiotic ampicillin. In this study, well diffusion method was used to determine the antibacterial activity of homoeopathic plant tincture Uva ursi against four uropathogenic bacterias (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae). Standard drug as positive control Ampicillin (Novadit injectable) used in concentration of 200mg/100ml and alcohol 70% was taken as negative control group. Inhibition zones were observed after 24-hour incubation. Standard drug Ampicillin showed significant antibacterial activity for Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae with zone of inhibition 40, 32, 30 and 22 mm respectively. Uva ursi mother tincture has maximum antibacterial activity against Staphylococcus aureus with zone of inhibition range up to 31 mm and least against Klebsiella pneumoniae zone of inhibition range up to 13mm, showed less susceptibility as compared to Staphylococcus aureus. Uva ursi 30C (potency) showed maximum inhibition against Staphylococcus aureus was 13mm and least against Klebsiella pneumoniae 4mm. The results showed that Uva ursi tincture have significant result against some common uropathogenic bacteria.
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