Abstract
On the plant surface the dimorphic fungus Ustilago maydis switches from budding to hyphal growth and differentiates appressoria. To get more insight into these highly regulated processes we report on the role of a conserved Ser/Thr kinase of the AGC kinase family, Aga1. U. maydis Aga1 could functionally replace Ypk1p in Saccharomyces cerevisiae. aga1 deletion mutants were affected in growth, cell wall integrity, mating as well as the ability to form appressoria and showed defects in actin organization and actin-dependent endocytosis. With respect to appressorium formation and endocytosis, the aga1 deletion phenotype could be mimicked by inhibiting the formation of actin filaments with Latrunculin A. These data suggest a critical role of Aga1 in F-actin organization during the morphological changes accompanying the development of appressoria.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
