Abstract
Abstract The acid-base balance in the blood has been studied in thirty-one women suffering from various forms of the toxemia of late pregnancy (nine hypertensive, fifteen nonconvulsive, and seven eclamptic patients). In general, the findings confirm the work of previous investigators by demonstrating a slight alkali deficit, without any significant change in the hydrogen-ion concentration, except in eclampsia, where a convulsive seizure is followed by a marked reduction in the bicarbonate and an associated, proportional lowering of the pH. On the basis of accumulated evidence, it would appear that the altered acid-base relationships of the blood in patients with pregnancy toxemia are of minor importance, and that any serious metabolic disturbances accompanying this disease entity must be sought in some tissue other than the blood.
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