Terminal Cancer and Bereavement

The Enigma of Hypertensive ESRD: Observations on Incidence and Trends in 18 European, Canadian, and Asian-Pacific Populations, 1998 to 2002

Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans

This study evaluates in-hospital, 30-day, and 1-year outcomes post-transcatheter aortic valve replacement (TAVR) in end stage liver disease (ESLD) and/or end stage renal disease (ESRD) compared with patients without these comorbidities. TAVR is an alternative to surgical aortic valve replacement in patients with ESLD and ESRD, though current outcomes data are limited. We compared 309 patients (N = 29 ESLD and/or ESRD, N = 280 control) age > 18 who underwent transfemoral TAVR from 2014 to 2020 have been compared. Patients with ESLD and ESRD were younger (69.9 ± 11.7 vs. 79.1 ± 9.8, p < .01) with higher STS-PROM scores (8.1 ± 6.7 vs. 4.6 ± 3.9, p < .01). ESRD and ESLD patients had similar rates of in-hospital major vascular complications (3.4% vs. 3.2%, p = .96), major bleeding events (3.4% vs. 3.2%, p = .95), and mortality (0.0% vs. 1.8%, p = .47). Mortality rates were similar at 30-days (3.4% vs. 2.1%, p = .65) with trend to higher mortality at 6-months (6.9% vs. 3.2%, p = .31) and 1-year (15.4% vs. 7.0%, p = .13). Readmission rates were higher in the ESLD and ESRD cohort at 6-months (53.2% vs. 28.6%, p < .01) and 1-year (65.4% vs. 41.0%, p = .02). One patient received dual kidney-liver transplant, 1 patient received a liver transplant, and 7 additional patients were listed for transplant. Patients with ESLD and/or ESRD who underwent TAVR had similar mortality at discharge and 30-days compared with patients without these comorbidities with a trend toward increased mortality at 1-year. This study suggests that TAVR is an option for aortic valve disease patients with ESRD and/or ESLD in order to remove cardiac barriers to liver or kidney transplant.

Long-term follow-up of patients with severe ANCA-associated vasculitis comparing plasma exchange to intravenous methylprednisolone treatment is unclear

Obesity Is Associated With Family History of ESRD in Incident Dialysis Patients

Objective To understand the needs for nursing services of terminal cancer patients from the perspective of patients' family members, for further development of strategy and providing a basis to improve the quality of terminal care. Methods Using the phenomenological approach of qualitative research, 16 family members of terminal cancer patients were interviewed with semi-structured interview outline. Colaizzi's analytical method was adopted to analyze the data, which were then organized into themes and sub-themes. Results The needs of the terminal cancer patients' families can be summarized into four subjects: to improve patients' quality of life, to offer psychological support, to maintain the terminal patients' hope and dignity, and to satisfy the needs of family members. Conclusions It is suggested that nurses should improve their clinical skills and symptom management skills to keep terminal patients comfortable. At the same time, nurses are supposed to enhance communication skills and focus on psychological support of patients. In addition, nurses should pay high attention to terminal cancer patients's piritual support and hope maintenance, helping patients and their families prepare for death in the Chinese traditional cultural context. Key words: Neoplasms; Hospice care; Family members; Nursing care; Qualitative research

Hormone replacement therapy in postmenopausal women with end-stage renal disease

Are There Consequences of Adolescent Blood Pressure on Kidney Function in Adulthood?

An Open-Label, Single-Arm, Phase 1 Study of the Pharmacokinetics (PK) and Safety of Carfilzomib in Patients with Relapsed Multiple Myeloma and End-Stage Renal Disease (ESRD)

End Stage Renal Disease after Cardiac Transplantation: An 11-Year National Cohort Study

GFR Decline as an End Point in Trials of CKD: A Viewpoint From the FDA

The renin–aldosterone axis in kidney transplant recipients and its association with allograft function and structure

Prevention of cardiovascular events in end-stage renal disease: Results of a randomized trial of fosinopril and implications for future studies

Clostridioides difficile Infection in Chronic Kidney Disease/End-Stage Renal Disease.

US Renal Data System 2022 Annual Data Report: Epidemiology of Kidney Disease in the United States.