Abstract

The cell division cycle is a coordinate and highly regulated series of events during which cells replicate their DNA content and then divide. Formally, the cell cycle has been divided in four phases: G1 (gap1 or presynthetic phase), S (synthetic phase), G2 (gap2 or postsynthetic phase) and M (mitosis). At the end of the mitotic events cells will choose between arrest (entering into the GO phase) or go through a new cell cycle. Each of these stages is characterized by a typical content of DNA: in G0 and in G1 phases cells have a diploid (2N) content of DNA, in G2 and M, they have a 4N DNA content, and in S phase they display an intermediate content of DNA.

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