Abstract

Neuropeptides play an important role for providing the specificity and complexity of interneuronal communications. To understand the function and regulation of peptidergic neurons, it is necessary to elucidate detailed cellular mechanisms of peptidergic neurons, including peptide production, receptor function and signal transduction. Our studies concern some of these mechanisms by investigating molecular aspects of mammalian tachykinin neuropeptides and their receptors. In this article, we describe some characteristic features of gene expressions of the tachykinin precursors and discuss our recent studies concerning the molecular nature of the tachykinin receptors.

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