Abstract

Hypertension is common in HFpEF and guidelines recommend an SBP<130 mmHg in HFpEF. Sacubitril/valsartan (S/V) significantly reduces SBP in HFrEF and HTN. In PARAGON-HF, we related baseline SBP (continuous and quartiles [<120, 120-129, 130-139, ≥140 mmHg]) to the primary outcome (CV death or

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