Abstract
A progressive ataxia in Suffolk sheep, appearing at 1/12–5 months of age after a period of clinical normality, is reported. The condition is regarded as hereditary and probably recessive, although it is not established that only a single locus is involved. Lesions were characterized by spheroids derived from the distal portions of axons. The bodies appeared to undergo hydropic swelling and eventual lysis. During the short periods of clinical observation, neither neuron necrosis nor tract degeneration were observed. The spheroids were distributed in a unique systemic pattern involving visual and proprioceptive pathways. Comparisons are made with other neuroaxonal dystrophies.
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