Abstract
Abstract We have synthesized and structurally characterized novel peroxovanadium(V) compounds containing amino acid derivatives as ancillary ligands; N-(4-imidazolylmethyl)-l-alanate (imala) and N-(4-imidazolylmethyl)-l-phenylalanate (imphe). The structure of the imala complex was determined using X-ray crystallography. These compounds stimulated the proliferation of H4IIEC3 rat hepatoma cells at low doses but were cytotoxic at high doses. They also exhibited insulin-mimetic effects.
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