Abstract
With the aim of obtaining ubiquinone analogues, a fraction of 5-n-alkyl(C19-C25)resoreinols isolated fromAzotobacter chroococcum 92 cells was converted by the action of diazomethane into mono-O-methyl derivatives, which were oxidized with m-chloroperbenzoic acid. The main oxidation products were characterized by spectrophotometric methods as 2-alkyl-6-methoxy-1,4-benzoquinones and 3-alkyl-5-methoxy-1,2-benzoquinomes. Both types of product accelerated the respiration of mitochondria on succinate in a similar way to natural CoQ10, but, in contrast to it, inhibited respiration on an NAD-dependent substrate.
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