Abstract

An efficient one-pot synthesis of a new series of spiro[benzo[h]quinoline-7,3′-indoline] was accomplished simply by the reaction of an isatin, naphthalen-1-amine and a CH-acid (N,N-dimethylbarbituric acid, barbituric acid, dimedone or 1,3-indandion) in acetic acid. During this process, the effects of solvent and temperature have been investigated on the yield of reactions. An efficient one-pot synthesis of a new series of spiro[benzo[h]quinoline-7,3'-indoline] was accomplished simply by the reaction of an isatin, naphthalen-1-amine and a CH-acid (N,N-dimethylbarbituric acid, barbituric acid, dimedone or 1,3-indandion) in acetic acid. During this process, the effects of solvent and temperature have been investigated on the yield of reactions.

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