Abstract

Sequential Ugi reaction between p-substituted benzaldehydes, 2-acetyl or 2-benzoylanilines, cyclohexyl or benzyl isocyanides, and 2-azidobenzoic acid, followed by a Staudinger/aza-Wittig cyclization in the presence of triphenylphosphine afforded pseudopeptidic [(5 H)-6-oxodibenzo[ b, f][1,5]diazocine-5-yl]arylglycinamides.

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