Abstract

2-Cyanoethyl phosphate employed as an efficient phosphorylating agent in the synthesis of nucleotide was found to be an excellent catalyst for the conversion of ribonucleosides to their 2', 3'-O-isopropylidene derivatives. This fact has led to the establishment of a novel, single-step conversion of ribonucleosides to 5'-ribonucleotides in a high yield using 2-cyanoethyl phosphate, acetone, pyridine, and dicyclohexylcarbodiimide without isolation of the 2', 3'-O-isopropylidene derivatives.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.