Abstract
Fluorescent nucleoside analogue bearing 3-amiobenzonitrile, which was a small and sensitive fluoresces probe to the microenvironment, was synthesized by a palladium-mediated Heck-type coupling reaction from iodated 3-aminobenzonitrile derivative and protected glycal. The spectroscopic study of the nucleoside analogue indicated that the fluorescence quenching caused in water and the fluorescent maximum was strongly dependent on the polarity of solvents.
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