Abstract
The reaction of imino esters of indole-series acids with acid hydrazides gave N(1)-acylamidrazones, which, during heating, were converted to 3,5-disubstituted 1H-1,2,4-triazoles containing indole fragments. Compounds of this type were also synthesized by the reaction of indolyl-containing 2,5-disubstituted 1,3,4-oxadiazoles with formamide. Condensation of 2,5-disubstituted 1,3,4-oxadiazoles with aniline gave 3,4,5-trisubstituted 4H-1,2,4-triazoles containing indolyl radicals. Cyclocondensation of N(1)-phenylamidrazones of indole-series acids with benzoyl chloride gave 1,3,5-trisubstituted 1H-1,2,4-triazoles.
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