Abstract

A preparative method of synthesis of 2-substituted thieno[2,3-d]pyrimidin-4-ones involving deamination of the corresponding 3-amino derivatives by sodium nitrite in acidic medium is proposed. A possible reaction mechanism is considered. Authors: S. G. Kazaryan, A. S. Noravyan, and G. A. Gevorkyan. English Translation in Chemistry of Heterocyclic Compounds , 1999, 35 (7), pp 825-828 http://link.springer.com/article/10.1007/BF02252109

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