Abstract
In this article, we have described the asymmetric cyclization of L-serinoates and N-benzyl L-serinoate with phosphoro(no-)dichloridates or their thio-analog, respectively, and we have investigated the asymmetric induction effect of the chiral carbon center on the forming of a chiral phosphorus center. The diastereomeric excess percentages (de%) of the desired products 2-oxo- and 2-thio-1,3,2-oxazaphospholidines, are obtained based on their 31P NMR data. In some cases, the cyclization products have been separated as pure diastereomers by column chromatography. Their configuration is preliminarily discussed. © 2000 John Wiley & Sons, Inc. Heteroatom Chem 11:187–191, 2000
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
