Abstract
AbstractThe synthesis of a series of 5‐phenylpyrrolo[1,2‐b][1,2,5]triazepin‐2(3H)‐ones 1 as potential anxiolytic agents is described. Benzoylation of 1‐phthalimidopyrrole, followed by hydrolysis, gave the 1‐amino‐2‐benzoylpyrroles 3. These were further functionalized to give the penultimate 1‐aminoacetamido‐2‐benzoylpyrroles 8 and 9, which were cyclized to the target pyrrolotriazepines 1.
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