Abstract
(2 S,3 S,1′ R)-2-(α-Methoxybenzyl)-3-phenyl-3-sulfanylpropionamides were diastereoselectively prepared by the reactions of N-cinnamoyl-4 S-isopropyl-5,5-dimethyloxazolidinethione with acetals in the presence of SnCl 4. The absolute configuration of the three newly created contiguous stereocenters was determined by the X-ray analysis of the disulfide. The amides were transformed into propanols by the reductive removal of the oxazolidinone moiety.
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