Abstract
AbstractAn efficient method for the preparation of 1‐acyl‐3,4‐dihydroquinazoline‐2(1H)‐thiones 5 has been developed. The reaction of N‐[2‐(azidomethyl)phenyl] amides 3, easily prepared by a three‐step sequence starting with (2‐aminophenyl)methanols, with Ph3P, followed by CS2, allowed generation of N‐[2‐(isothiocyanatomethyl)phenyl]‐amide intermediates 4, which underwent cyclization on treatment with NaH to furnish the corresponding desired products in generally good yields.
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