Abstract
Abstract The key intermediates for 11-methyl- and 11,11-dimethylprostaglandins corresponding to Corey’s lactone were synthesized via the Wittig reaction of dimethyl 2-substituted-4,5-dioxocyclopentane-1,3-dicarboxylate with stable ylides. 11,11-Dimethylprostaglandin E2 was then synthesized.
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