Synthesis of α-Aminophosphonates Derivatives by Using Novel Nano-Catalyst through Kabachnik-Fields Reaction

Abstract

The novel Nano-catalyst (PAni-Mn) as the first multifunctional catalyst is described for efficient synthesis of α-Aminophosphonates by Kabachnik-Field reaction. This reaction is a Multicomponent reactions in which three- components i e. substituted aldehyde, aniline and dialkylphosphite are combining to form α-Aminophosphonates. The four α-Aminophosphonates were synthesized in good to high yield under solvent free condition at room temperature. The novel Nano-catalyst i.e. Doped Polyaniline with Manganese (PAni-Mn) has been synthesized first and characterized by elemental analysis FT-IR, SEM, TEM, X-ray diffraction technique. This catalyst provides high surface area, increase catalytic activity, easily separated and recycled. It increases the yield of α-Aminophosphonates. α-Aminophosphonates are bioisosteres of amino acids analogous, which has important application in Industrial, Agricultural and Medicinal field, due to their biological and physical properties, They are also use full as synthetic intermediates..