Synthesis, crystal structure and fluorescence spectrum of some new 1,2,3-triazol-xanthen-3-one derivatives

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Some new compounds 9-(1-aryl-5-methyl-1 H -1,2,3-triazol-4-yl)-6-hydroxy-3 H -xanthen-3-one 7a -j have been synthesized for new fluorescence probe material. Their fluorescence and ultraviolet-visible spectra have been studied. Their structures are established by MS, IR and 1 H NMR spectral data. The structure of title compound 7c has been identified by X-ray diffraction. C 22 H 14 C1N 3 O 3 , belongs to triclinic system, space group P ī with a = 8.296(4), b = 9.726(5), c = 11.976(6) Å, α = 90.953(7), β = 105.081(7), γ = 100.693(8)º, V = 914.7(8)Å 3 , Z = 2, Dc = 1.466 Mg/m 3 , F (000) = 416.0 and μ = 0.240 mm –1 . The title compound has a weaker inhibiting HIV-1 protease than indinavir.