Abstract
ABSTRACT Triazole and fused heterocyclic triazole derivatives like Schiff bases, thiadiazoles, thiadiazepine, thiadiazine etc. were synthesized and characterized by IR, MS and 1 H NMR. The triazole derivatives were evaluated for their antibacterial activity against the gram-positive bacteria B. megaterium and S. aureus , the gram-negative bacteria E. aerogenes and P. Aeruginosa using DMSO as a solvent. INTRODUCTION Heterocycles are in the center of research due to their versatile application 1 . The triazole ring system is of particular interest especially within the realm of medicinal chemistry because of their versatile biological activity and clinical applications 2,3 . A number of triazole derivatives are associated with good biological as well as pharmacological activities like antibacterial 4 , anti-inflammatory 5 , antihypertensive 6 , antifungal 7 , anticancer 8 and antitumor 9 activity. Fused heterocyclic triazoles also possess important clinical applications
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