Synthesis and structure of new types of organogermanium compounds containing α-amino acid or α-aminophosphonic acid moieties

Abstract

A series of germasesquioxides and germatranes containing α-amino acid or α-aminophosphonic acid moieties was synthesized by the reaction of β-trichlorogermylpropionyl chloride with α-amino acid esters or α-aminophosphonates. The structures of all products were confirmed by 1H NMR, 31P NMR, and IR spectra, and elemental analyses. The intramolecular monocyclic penta-coordinated structure of the trichlorogermyl intermediate was determined by X-ray diffraction. The X-ray analyses showed that the geometry about the germanium atom was a slightly distorted trigonal bipyramid, and a coordinate covalent bond exists between the oxygen and the germanium atoms. © 1999 John Wiley & Sons, Inc. Heteroatom Chem 10: 73–78, 1999