Abstract
ABSTRACTIn this study, polycaprolactone (PCL)/polyethylene glycol diacrylate (PEGDA)/Copper oxide-exchange zeolites (Z-CuO) were synthesised via the semi-interpenetrating network. UV-Vis spectroscopy, FTIR, and SEM analyse the chemical structure of films, ion-exchange of zeolite and copper, and morphological study of the surface, respectively. Moreover, gel fraction, swelling, and water vapour transmission, and mechanical properties of the networks were evaluated. Results showed that increasing the ratio of PEGDA to PCL was followed by rising swelling ratio and water vapour transmission. In addition, adding Z-CuO to polymer structure improved its mechanical properties. Finally, antibacterial and cytocompatability of the films were tested by agar disc diffusion method and MTT assay, respectively. The antibacterial activity results indicated that the film with Z-CuO had the highest antibacterial activities against Staphylococcus aureus and Escherichia coli bacteria. The MTT results confirmed the cytocompatible nature of PEGDA/PCL/Z-CuO films. Thus, the results indicated that the PEGDA/PCL/Z-CuO films have the potential of being used wound healing.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
